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enquirySARM Cardarine Gw-501516/Gw501516 99.9% Purity CAS: 317318-70-0
Cardarine (GW-501516) binds to the PPAR receptor, specifically a group of nuclear receptors (sensors that detect thyroid and steroidal hormones in the body) that initiates the PGC-1a enzyme.
This action leads to gene expression, specifically genes that revolve around energy expenditure.
Studies involving GW-501516 have shown to increase the metabolism of fatty acids in rats. It was also shown in the same studies to reduce the odds of obesity despite poor eating habits as well as prevent Type-2 diabetes.
Cardarine was also shown to increase HDL (good cholesterol) and decrease LDL (bad cholesterol) in a study using monkeys. The effects seemed to hold true with or without exercise.
What is ENDUROBOL (GW-501516)?
ENDUROBOL (GW501516 or GSK-516) is a PPARδ receptor agonist that was previously investigated for drug use.
ENDUROBOL is a selective agonist with high affinity and it is very potent. Various studies on this PPAR receptor in lab indicates that it regulates the various proteins that the body uses for energy.
ENDUROBOL can help to reduce and even reverse various problems in men who are obese or that have symptoms of pre-diabetes due to problems with their metabolism.
The use of GW-501516 is viable treatment for reducing obesity and various conditions that are linked to it.
Product name:GW-501516
GW501516 CAS No: 317318-70-0
GW501516 MF: C21H18F3NO3S2
GW501516 MW:453.4977
Customized: Non-Customized
GW501516 Suitable for: Elderly, Adult
GW501516 Purity: >99%
GW501516 Usage :It had been investigated as a potential treatment for obesity, diabetes, dyslipidemia and cardiovascular disease. GW501516 could be used by athletes as an ergogenic performance enhancing drug.
GW501516 Function:
GW501516 could be used by athletes as an ergogenic performance enhancing drug that was not currently controlled by regulations or detected by standard tests.
One of the main researchers from the study onenhanced endurance consequently developed a urine test to detect the drug, and made it available to the International Olympic Committee.
How it works?
ENDUROBOL is a selective agonist (activator) of the PPARδ receptor. It displays high affinity (Ki = 1 nM) and potency (EC50 = 1 nM) for PPARδ with > 1000 fold selectivity over PPARα and PPARγ.
It activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue, and GW 501516 has been demonstrated to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation.
It has been proposed as a potential treatment for obesity and related conditions, especially when used in conjunction with a synergistic compound AICAR, as the combination has been shown to significantly increase exercise endurance in human.
GW501516 Dosages and Suggestion:
Recommended maximum dose ENDUROBOL is 10 mg per day but many people use as much as 20 mg per day to burn as much fat as they can in in the 8 week cycle.
There are two main uses with GW-501516. The first and most common use is that of increased endurance. GW has been banned for professional athletes due to the unfair advantage it provides to endurance athletes.
Anyone want a drastic increase in endurance will find that GW truly shines in this aspect. It takes effect very quickly and the results can be staggering. A common dose of 10 mg day will provide a significant increase in endurance.
The second common usage with GW is that of fat loss. Many users turn to GW as it has shown to melt off fat while still being non-catabolic. You will find that you can still hold on to some muscle as you are losing fat.
It helps when you are running it in conjunction with SARMS Ostarine and S4, to hold on to as much muscle as possible. A dosage of 10 mg a day will provide good amounts of fat loss, but an increase to 20 mg a day will provide much more in this area.
GW 501516 can be ran in 8 week cycles, but as with any other steroid or supplement, it should be cycled properly to avoid any possible side effects and the keep it as effective as possible.
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